Society for Actinomycetes Japan The
Society for
Actinomycetes
Japan



Established in 1955 and recognized in 1985 by the Science Council of Japan.
[Japanese Page]

2017 Annual Meeting of SAJ will be held at Wakasato Municipal Cultural Hall, Nagano on Sep. 7 to 8.
2017 Annual Meeting of SAJ (Sep. 7-8, Nagano)

Outline of SAJ

Newsletter [Up]
(Actinomycetologica)

Official Journal

JA Free Access (members only)

Digital Atlas of Actinomycetes Ver. 2

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Topics
[2017/06/05] Home page of 2017 Annual Meeting of SAJ has been opened.
[2017/01/17] Newsletter Actinomycetologica 30(2) is out.
[2016/07/06] Newsletter Actinomycetologica 30(1) is out.
[2016/06/17] The ISBA18 webpage is now live on the internet.
[2016/05/25] [GIM2016] Abstract submission: 1 June 2016
[2015/12/25] Official newsletter Actinomycetologica Vol.29 No.2 is out.
[2015/10/7] Professor Satoshi Omura, an honorary member of the SAJ, was awarded the 2015 Nobel Prize in Physiology or Medicine.
Natural Product Discovery & Development in The Post Genomic Era (San Diego, Jan. 11-14, 2015)
ISBA'17 (Kusadasi, Turkey, Oct. 8-12, 2014)
ESF-EMBO symposium on the Synthetic Biology of Antibiotic Production II (Spain, 8/30-9/4 2014)
JA's AOP web feed

Total synthesis of (+)-lysergic acid July 19 2017. doi:10.1038/ja.2017.80 Rentaro Kanno, Satoshi Yokoshima, Motomu Kanai & Tohru Fukuyama

Allostreptomyces indica sp. nov., isolated from India July 19 2017. doi:10.1038/ja.2017.82 Amit Kumar Sahu, Syed Raziuddin Quadri, Dayanand Agasar, Jamal Al Ruwaili, Wen Jun-Li & Syed G Dastager

Novel p-terphenyl glycoside with a rare 2,6-dideoxyhexopyranose moiety from Actinomycete strain SF2911 that inhibits cancer cell migration July 19 2017. doi:10.1038/ja.2017.83 Liyan Wang, Menjie Li, Jianqiang Tang, Yinzhi Lin, Kulrawee Sidthipong, Naomi Sumida, Nobuaki Kushida & Kazuo Umezawa

Discovering potential Streptomyces hormone producers by using disruptants of essential biosynthetic genes as indicator strains July 19 2017. doi:10.1038/ja.2017.85 Nguyen B Thao, Shigeru Kitani, Hiroko Nitta, Toshiya Tomioka & Takuya Nihira

New 12,8-Eudesmanolides from Eutypella sp. 1–15 July 19 2017. doi:10.1038/ja.2017.89 Yuezhou Wang, Yue Wang, An-an Wu, Lei Zhang, Zhiyu Hu, Huiying Huang, Qingyan Xu & Xianming Deng

New anti-inflammatory metabolites produced by Streptomyces violaceoruber isolated from Equus burchelli feces July 12 2017. doi:10.1038/ja.2017.75 Jian Ma, Hui Lei, Xiu Chen, Xiaoxu Bi, Yi Jiang, Li Han & Xueshi Huang

Insight into synergetic mechanisms of tetracycline and the selective serotonin reuptake inhibitor, sertraline, in a tetracycline-resistant strain of Escherichia coli July 12 2017. doi:10.1038/ja.2017.78 Lili Li, Sofie Kromann, John Elmerdahl Olsen, Søren Wedel Svenningsen & Rikke Heidemann Olsen

A quinolinol-based small molecule with anti-MRSA activity that targets bacterial membrane and promotes fermentative metabolism July 12 2017. doi:10.1038/ja.2017.79 Dhanalakshmi R Nair, Ji Chen, João M Monteiro, Michaele Josten, Mariana G Pinho, Hans-Georg Sahl, Jimmy Wu & Ambrose Cheung

Virgisporangium myanmarense sp. nov., a novel motile actinomycete isolated from an anthill soil in Myanmar July 12 2017. doi:10.1038/ja.2017.81 Hideki Yamamura, Shoya Miyazaki, Kodai Ikoma, Youji Nakagawa, Moriyuki Hamada, Misa Otoguro, Tomohiko Tamura, Katsuhiko Ando, Nyunt Phay & Masayuki Hayakawa

Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety July 5 2017. doi:10.1038/ja.2017.59 Ko Kumura, Yoshinari Wakiyama, Kazutaka Ueda, Eijiro Umemura, Takashi Watanabe, Mikio Yamamoto, Takuji Yoshida & Keiichi Ajito

A brief history of antibiotics and select advances in their synthesis July 5 2017. doi:10.1038/ja.2017.62 Kyriacos C Nicolaou & Stephan Rigol

Effect of the meropenem MIC on the killing activity of meropenem and polymyxin B in combination against KPC-producing Klebsiella pneumoniae July 5 2017. doi:10.1038/ja.2017.73 Brandon Kulengowski, Jeffrey J Campion, David J Feola & David S Burgess

Allantopyrone A interferes with multiple components of the TNF receptor 1 complex and blocks RIP1 modifications in the TNF-α-induced signaling pathway July 5 2017. doi:10.1038/ja.2017.74 Hue Tu Quach, Riho Tanigaki, Junpei Yokoigawa, Yuriko Yamada, Masamitsu Niwa, Seiya Hirano, Yoshihito Shiono, Ken-ichi Kimura & Takao Kataoka

Trichopeptides A and B, trichocyclodipeptides A–C, new peptides from the ascomycete fungus Stagonospora trichophoricola July 5 2017. doi:10.1038/ja.2017.76 Zhengkun Chen, Xiuli Xu, Jinwei Ren, Wenzhao Wang, Xingzhong Liu & Erwei Li

Toward the total synthesis of luminamicin; an anaerobic antibiotic: construction of highly functionalized cis-decalin containing a bridged ether moiety July 5 2017. doi:10.1038/ja.2017.77 Hiroyasu Ando, Aoi Kimishima, Motoyoshi Ohara, Tomoyasu Hirose, Takanori Matsumaru, Hirokazu Takada, Keisuke Morodome, Takehiro Miyamoto, Akihiro Sugawara, Satoshi Ōmura & Toshiaki Sunazuka

Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity June 28 2017. doi:10.1038/ja.2017.60 Yoshiaki Takahashi, Eijiro Umemura, Yoshihiko Kobayashi, Shoichi Murakami, Toru Nawa, Akihiro Morinaka, Toshiaki Miyake & Masakatsu Shibasaki

A 2,4′-linked tetrahydroxanthone dimer with protein tyrosine phosphatase 1B inhibitory activity from the Okinawan freshwater Aspergillus sp. June 28 2017. doi:10.1038/ja.2017.72 Henki Rotinsulu, Hiroyuki Yamazaki, Tomohito Miura, Satomi Chiba, Defny S Wewengkang, Deiske A Sumilat & Michio Namikoshi

Coumarin–benzimidazole hybrids as a potent antimicrobial agent: synthesis and biological elevation June 21 2017. doi:10.1038/ja.2017.70 L Ravithej Singh, Srinivasa Rao Avula, Sneha Raj, Akanksha Srivastava, Gopala Reddy Palnati, C K M Tripathi, Mukesh Pasupuleti & Koneni V Sashidhara

Antimicrobial sulfonamides clear latent Kaposi sarcoma herpesvirus infection and impair MDM2–p53 complex formation June 14 2017. doi:10.1038/ja.2017.67 Fabrizio Angius, Enrica Piras, Sabrina Uda, Clelia Madeddu, Roberto Serpe, Rachele Bigi, Wuguo Chen, Dirk P Dittmer, Raffaello Pompei & Angela Ingianni

A three-component coupling approach to the ACE-ring substructure of C19-diterpene alkaloids June 14 2017. doi:10.1038/ja.2017.69 Kosuke Minagawa, Daisuke Urabe & Masayuki Inoue

D-cycloserine increases the effectiveness of vancomycin against vancomycin-highly resistant Staphylococcus aureus June 7 2017. doi:10.1038/ja.2017.56 Fumiaki Tabuchi, Yasuhiko Matsumoto, Masaki Ishii, Keita Tatsuno, Mitsuhiro Okazaki, Tomoaki Sato, Kyoji Moriya & Kazuhisa Sekimizu

The salicylidene acylhydrazide INP0341 attenuates Pseudomonas aeruginosa virulence in vitro and in vivo June 7 2017. doi:10.1038/ja.2017.64 Pia Uusitalo, Ulrik Hägglund, Elin Rhöös, Henrik Scherman Norberg, Mikael Elofsson & Charlotta Sundin

Albiducins A and B, salicylaldehyde antibiotics from the ash tree-associated saprotrophic fungus Hymenoscyphus albidus June 7 2017. doi:10.1038/ja.2017.66 Sandra Halecker, Frank Surup, Halvor Solheim & Marc Stadler

Synthesis and structure–activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities May 31 2017. doi:10.1038/ja.2017.54 Yoshinari Wakiyama, Ko Kumura, Eijiro Umemura, Kazutaka Ueda, Takashi Watanabe, Keiko Yamada, Takafumi Okutomi & Keiichi Ajito

Cladomarine, a new anti-saprolegniasis compound isolated from the deep-sea fungus, Penicillium coralligerum YK-247 May 31 2017. doi:10.1038/ja.2017.58 Konami Takahashi, Kazunari Sakai, Yuriko Nagano, Sakiko Orui Sakaguchi, Andre O Lima, Vivian H Pellizari, Masato Iwatsuki, Kiyotaka Takishita, Kenichi Nonaka, Katsunori Fujikura & Satoshi Ōmura

5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity May 31 2017. doi:10.1038/ja.2017.61 Akihiro Sugawara, Hitomi Maruyama, Sho Shibusawa, Hidehito Matsui, Tomoyasu Hirose, Ayumi Tsutsui, Robrecht Froyman, Carolin Ludwig, Johannes Koebberling, Hideaki Hanaki, Gerd Kleefeld, Satoshi Ōmura & Toshiaki Sunazuka

NC1404, a novel derivative of Bleomycin with modified sugar moiety obtained during the preparation of Boningmycin May 31 2017. doi:10.1038/ja.2017.63 Xin Qi, Xinwei Wang, Hao Ren, Feng Zhang, Xiumin Zhang, Ning He, Wenqiang Guo, Ruxian Chen, Yunying Xie & Qiyang He

Inhibition of DNA replication in Staphylococcus aureus by tegaserod May 31 2017. doi:10.1038/ja.2017.65 Christopher J Lacriola, Shaun P Falk & Bernard Weisblum

A novel polycyclic meroterpenoid with aldose reductase inhibitory activity from medicinal mushroom Ganoderma leucocontextum May 24 2017. doi:10.1038/ja.2017.57 Jinjin Zhang, Ke Ma, Hongyu Chen, Kai Wang, Weiping Xiong, Li Bao & Hongwei Liu

Novel antibiotic screening methods to awaken silent or cryptic secondary metabolic pathways in actinomycetes April 26 2017. doi:10.1038/ja.2017.51 Hiroyasu Onaka

Verification of oligomycin A structure: synthesis and biological evaluation of 33-dehydrooligomycin A April 19 2017. doi:10.1038/ja.2017.48 Lyudmila N Lysenkova, Oleg Y Saveljev, Natalya E Grammatikova, Vladimir B Tsvetkov, Olga B Bekker, Valery N Danilenko, Lyubov G Dezhenkova, Eugene E Bykov, Olga A Omelchuk, Alexander M Korolev & Andrey E Shchekotikhin

Related Links
FramePlot 2.3 - protein-coding region prediction tool
2ndFind - secondary metabolite biosynthetic gene discovery tool
Codon Usage Table of The Genus Streptomyces (GenBank R.118)
Genome:
Streptomyces griseus IFO 13350
Streptomyces avermitilis MA-4680
Streptomyces coelicolor A3(2)
Saccharopolyspora erythraea NRRL 2338
Mycobacterium tuberculosis H37Rv
Corynebacterium diphtheriae
Corynebacterium efficiens YS-314
Noardia farcinica IFM 10152
Rhodococcus erythropolis PR4
Rhodococcus opacus B4
Rhodococcus jostii RHA1
Frankia spp.
National BioResource Project (NBRP)
Journal of Antibiotics
Novel Antibiotics DataBase [Download] [Search]
NCBI Taxonomy